DISITAMAB VEDOTIN COMBINED WITH PYROTINIB AS SALVAGE TREATMENT IN HER-2-AMPLIFIED TREATMENT REFRACTORY METASTATIC COLORECTAL CANCER: A CASE REPORT

Disitamab vedotin combined with pyrotinib as salvage treatment in Her-2-amplified treatment refractory metastatic colorectal cancer: a case report

BackgroundHuman epidermal growth factor receptor 2 (HER-2) amplification has been identified in approximately 3% of patients with metastatic colorectal cancer (mCRC).Owing to the lack of established anti-ERBB2 therapeutic approaches, mCRC patients with Her-2 amplification rarely receive targeted treatments.Moreover, conventional chemotherapy regime

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Sorption of petroleum products with natural sorbents

This article presents the results of a study of cleaning the water surface from contamination with petroleum products.Kulantaussky vermiculite, the birthplace of the Turkestan region, was studied as a sorbent.Studies have shown that the modified vermiculite yaya vape is able to retain the sorbed oil up to 2 days after the expiration of the main sor

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